4300
Learn more about the [INSERT INSTRUMENT DESCRIPTION HERE]

APPLICATIONS FOR THE 4300

Click any of the applications below to see a detailed description

DNA SEQUENCING


Application Overview

Since their introduction more than 10 years ago, LI-COR infrared DNA analyzers have been characterized by very long sequencing reads with high accuracy. LI-COR's system delivers 1000 - 1200 bp per sample (model 4300L) or 800 bp per sample (model 4300S) with 99% accuracy*.

But long reads are only part of the story. Protocols like Simultaneous Bi-directional Sequencing (SBS™) make DNA sequencing easier by cutting your workload and reducing reagent expense by 50%. Bi-directional reactions include both forward and reverse primers and produce over 1000 bases (model 4300L) from each end of a template.

The 4300 DNA analyzer includes basic sequencing software run from a standard Internet browser designed to meet the needs of users who have an occasional need for DNA sequencing. For moderate to high sequencing demands, or just greater ease of use, LI-COR's e-Seq™ software gives you a higher level of automation, strong editing tools, and automated reporting that exports files to standard databases or submits files for BLAST searches.

To view the DNA Sequencing brochure click here.

Advantages

Infrared DNA sequencing on a 4300 System, combined with e-Seq software offers these cost advantages:

  • Sequence yield is greater than 2000 bases per reaction

  • Low maintenance operation with infrared technology

  • Faster results and less labor using e-Seq software

  • Economical expansion without adding additional computers

  • High accuracy data are quicker and easier to assemble

  • 50% reduction in reaction costs with bi-directional sequencing protocols

PubMed

Publishing with LI-COR data?

Cloning, sequencing, and expression of the Zymomonas mobilis phosphoglycerate mutase gene (pgm) in Escherichia coli.
L P Yomano, R K Scopes, and L O Ingram
J. Bacteriol., Jul 1993; 175: 3926 - 3933.

To see other publications on sequencing click here.