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Category Archives: IRDye Reagents
Click Chemistry Reagents from LI-COR® for Biomolecule Labeling
Biomolecule labeling continues to be a cornerstone feature of many in vitro and in vivo biological experiments. Click Chemistry has recently emerged as a convenient, versatile, and reliable method for labeling a wide variety of molecules for applications ranging from … Continue reading
Click Chemistry Reagents Labeled with DBCO Groups Allow for Copper-Free Biomolecule Labeling Reactions
LI-COR now offers Click Chemistry reagents for copper-catalyzed and copper-free methods. One group of products within this portfolio includes IRDye® infrared dyes labeled with DBCO groups, which can be used for copper-free methods. The dibenzocyclooctyne group (DBCO) allows copper-free Click … Continue reading
Create a Complete Molecular Imaging Workstation
Combining the Odyssey® CLx Infrared Imaging System with the Pearl® Impulse Small Animal Imaging System creates a versatile workstation for in vivo and in vitro imaging. BrightSite™ Optical Imaging Agents or probes developed using IRDye® infrared dyes can be used … Continue reading
Posted in IRDye Reagents, In Vivo Imaging System and Applications, Odyssey Imaging Systems
Tagged brightsite imaging agents, in vitro assays, in vivo imaging, in vivo imaging workstation, infrared dyes, irdye optical probes, molecular imaging, odyssey applications, pearl applications, pearl impulse small animal imaging system, preclinical research, probe validation, small animal imaging, workstation
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NEW! IRDye® Goat Anti-Mouse IgM Secondary Antibodies from LI-COR®!
Our IRDye secondary antibody line is growing! We have recently added IRDye Goat anti-Mouse IgM (μ chain specific) secondaries labeled with: IRDye 800CW (PN 926-32280) IRDye 680RD (PN 926-68180) or IRDye 680LT (PN 926-68080). Just like all of the LI-COR … Continue reading
Posted in IRDye Reagents, Proteomics Applications, Reagents, Western Blotting
Tagged 700nm channel secondary antibodies, cell based assays, dye-labeled antibody conjugates, irdye 680lt, irdye 680rd, irdye 800cw, irdye infrared dyes, labeled secondary antibodies, li-cor western blots, li-cor western blotting, licor western blotting, multiplexing, near-infrared fluorescent reagents, secondaries, secondary antibody conjugates, western blots
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New! Optical Probe for Tumor Imaging – IRDye® 800CW YC-27
IRDye 800CW YC-27 (P/N 926-27000) is a near-infrared dye-labeled imaging agent specifically designed to target prostate specific membrane antigen (PSMA), also known as folate hydrolase I or glutamate carboxypeptidase II. This small molecule can be used as an optical imaging … Continue reading
Posted in Cancer Research, IRDye Reagents, In Vivo Imaging System and Applications, Reagents
Tagged cancer imaging, dna-protein interactions, in vitro imaging, near-infrared dyes, near-infrared fluorescent dyes, near-infrared fluorescent reagents, pearl impulse small animal imaging system, preclinical evaluation of tumors, preclinical research, prostate cancer, psma expressing tissues, targeting agent for prostate cancer, tissue section imaging, tumor imaging
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Use IRDye® Labeled Oligonucleotides for Safer, Faster EMSA/Gel Shift Assays
The EMSA (electrophoretic mobility shift assay) is used to study protein:DNA complexes and interactions. Protein:DNA complexes migrate more slowly than unbound linear DNA on a non-denaturing gel, causing a “shift.” Also called “gel shift” or “gel retardation” assays, EMSA can … Continue reading
In-Cell Western™ Assay Application: Response of COS-7 Cells to Hydroxyurea
Application: Detecting phospho-p53 in COS cells in response to Hydroxyurea The response of COS-7 cells to increasing doses of hydroxyurea was measured by a specific antibody (Anti-phospho-p53 from Cell Signaling Technology, P/N 9286) that detects phosphorylated-p53 (Ser16). Total ERK1 was … Continue reading
Posted in Cancer Research, IRDye Reagents, Odyssey Imaging Systems, Proteomics Applications
Tagged cell based assays, immunofluorescent assays, in-cell ELISA, licor odyssey imagers, near-infrared fluorescent reagents, odyssey applications, protein phosphorylation, signal transduction
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Now Use the Same Primary Antibody for Immunoprecipitation AND Western Blotting!
LI-COR® has just rolled out a new way that the recently-released Quick Western Kit – IRDye® 680RD (see Would you like to save at least 90 minutes the next time you do a Western blot?) can be used in your … Continue reading
Posted in IRDye Reagents, Odyssey Imaging Systems, Proteomics Applications, Western Blotting
Tagged fast western blotting, immunoprecipitation, IP, irdye infrared dyes, li-cor western blots, li-cor western blotting, licor odyssey imagers, near-infrared fluorescent reagents, odyssey applications, quick western kit, western blots, Western blotting kits
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Studying bone growth, changes, tumors? Try IRDye® BoneTag™ Optical Probes.
IRDye BoneTag optical imaging agents are tetracycline derivatives that incorporate into mineralizing bone. Structural imaging of bone can be used to more precisely localize an area of disease. A second disease-specific targeting agent with a spectrally-distinct fluorescent label can be … Continue reading
Try Microscopy with Near-Infrared Fluorescent Dyes For Outstanding Images
Do you know that LI-COR® near-infrared dyes and reagents can be used to perform microscopy? Absolutely! While we do not sell microscopes or offer microscopic equipment, we have evaluated the near-infrared detection capabilities of microscopes from several manufacturers, particularly in … Continue reading
