Category Archives: Neuroscience

Odyssey® References for Neuroscience Research Applications

Odyssey Infrared Imaging Systems and LI-COR® reagents have been used for research applications in many different disciplines, including neuroscience, neurobiology, Alzheimer’s Disease, Parkinson’s and more. This week the Society for Neuroscience is holding its annual meeting in New Orleans, LA. … Continue reading

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Monitor Protein Levels and Phosphorylation with Quantitative Multiplexed Western Blots

Molecular profiling reveals diversity of stress signal transduction cascades in highly penetrant Alzheimer’s disease human skin fibroblasts. Mendonsa, G., et al. PLoS ONE 4(2): e4655. doi:10.1371/journal.pone.0004655 Aberrant signal transduction is associated with Alzheimer’s disease (AD). In skin fibroblasts of AD … Continue reading

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Receptor-based Binding and Competition Assays with Infrared Fluorescence

What is an On-Cell Western Assay? It’s a cell-based assay that enables quantitative monitoring of cell surface protein expression. The On-Cell Western assay offers the ability to: Detect and quantify target proteins localized to the cell surface Quantify ligand binding … Continue reading

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How Can You Use Quantitative Cell Signaling Analysis in Your Research? How About for IC50 Determinations?

In a previous post, I talked about how In-Cell Western™ assays could be used when studying apoptosis. So, you may be asking yourself, for what other applications can quantitative cell signaling analysis be used? GREAT QUESTION!! Well, in-Cell ELISAs (as … Continue reading

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