Dr. Geir Bjørkøy is a Professor at the University College of Sør-Trøndelag and CEMIR Centre of Exellence, NTNU, in Trondheim, Norway. He studies the molecular biology of cancer. Bjørkøy’s major focus uses Western blotting to study phosphorylation in the PI3 Kinase pathway.
Dr. Bjørkøy’s lab uses the Odyssey Imager to examine the differences in phospho-Akt levels in the cross-sections of tumors grown in nude mice and tumor samples from patients. According to Bjørkøy, “Quantifying tumor size reduction will be crucial for future cancer diagnostics and therapies.”
Bjørkøy combines his work on the Odyssey Imager with confocal microscopy by mixing in secondary antibodies that can be detected in the visible light spectra. After scanning the whole tissue section on the Odyssey Imager and gathering data, Bjørkøy uses a confocal microscope to examine particular sections in more detail. He looks at how specific inhibitors affect tumor growth.
Bjørkøy’s innovation using the Odyssey Infrared Imager for immunohistochemistry analysis, and exploring future quantitative cancer diagnostics are just a couple of the reasons we are proud to call him an “Odyssey Expert.”
Read Dr Bjørkøy’s recently published paper utilizing the Odyssey Infrared Imaging System:
- Metabolic biomarkers for response to PI3K inhibition in basal-like breast cancer
Moestue SA, Dam CG, Gorad SS, Kristian A, Bofin A, Mælandsmo GM, Engebråten O, Gribbestad, IS, Bjørkøy G.
Breast Cancer Research (Feb 2013) 15: R16. doi:10.1186/bcr3391