Dr Patrick Kiely is a Principal Investigator and Senior Scientist in Professor Rosemary O’Connor’s laboratory, in the Department of Biochemistry. The lab is located in the BioSciences Institute at the University College Cork in Ireland.
Dr Kiely studies cell migration, a process that involves a network of tightly regulated signaling pathways. Breakdowns in this regulation contribute to immune disorders, and are fundamental to the invasiveness of many cancers (see my blog post on 17-Apr-12 regarding invasiveness in cancers). Dr Kiely is investigating the molecular mechanisms of tumor cell migration and invasiveness.
Using arrays of immobilized target peptides, Dr Kiely studies the protein-protein interactions that occur during cell migration. He identifies proteins that compete with one another for binding to a target protein, and examines their binding preferences.
“We couldn’t do this without the Odyssey’s ability to do dual detection of two different colors, based on detection of two different proteins. So that’s proved to be really cool,” says Kiely. “The time that the Odyssey saves us in Western Blot techniques is critical, it cuts down our workload dramatically.”
For more information on Dr Kiely’s research and a list of publications resulting from work on the Odyssey, go to this customer testimonial.
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