Infrared Detection for Highest Sensitivity

The high sensitivity of infrared detection is criticial because the LI-COR 4300 System maintains a good signal-to-noise ratio even with the signal loss due to exonuclease activity in Ecotilling. The inherent low background of infrared detection compared to visible detection, combined with LI-COR’s IRDye® Infrared Dyes, results in another key advantage – wide dynamic range. Wide dynamic range is critical for resolving the weaker bands of polymorphisms along with strong wild type bands. Low infrared background from amplification artifacts makes it easy to resolve polymorphisms with the 4300 System.