Biotechnology
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LI-COR Biosciences 800-645-4267 402-467-0700 402-467-0819
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LI-COR Introduces New Line of IRDye® Protease Assay Kits
January 31, 2008: LI-COR Biosciences introduces a new line of protease detection assays including a general Casein protease substrate and assays for detection of HIV-1 and β-Secretase.
Casein a protein found in milk, is over-labeled with IRDye 800RS producing a quenched substrate for use in protease assays. This near-infrared protease substrate has significant advantages compared to protease assays using visible fluorescence.
The IRDye® HIV-1 Protease Assay Kit and IRDye β-Secretase Assay Kit (BACE-1) are near-infrared fluorescence energy transfer (NIR-FRET) based assays that introduce a new platform with enhanced sensitivity for protease activity detection. These assays utilize a novel, spectrally matched NIR dye FRET pair, IRDye 800CW and the new IRDye QC-1 Quencher, in conjunction with a LI-COR Odyssey® or Aerius® NIR imaging system for detection.
LI-COR Biosciences is a leader in the design, manufacture, and marketing of integrated infrared instrument systems and reagents for biotechnology and drug discovery research. Founded in 1971, the privately held company is based in Lincoln, Nebraska, with subsidiaries in Germany and the United Kingdom. LI-COR systems are used in over 100 countries and are supported by a global network of offices and distributors.
