ODYSSEY MousePOD®

One Probe Simplifies Discovery

The Odyssey System with the MousePOD in vivo Imaging Accessory is a complete solution for in vitro, in vivo, and ex vivo analysis – all on a single, affordable platform.

Odyssey MousePOD

• Snaps into place over Odyssey® scanning surface
• Install and remove as needed
• Accommodates up to 3 mice
• Facilitates gas anesthesia
• Label your own probe, or try our ready-to-use IRDye imaging agents

One Probe Simplifies Discovery

Use the Odyssey system and IRDye® near-infrared dyes for all the steps in your molecular imaging workflow. Performing all your studies with the same probe and fluorescent label saves time, and makes data interpretation more consistent.

• Cell-based assays

• Test the binding and specificity of your probe with in vitro cell-based assays, before you begin animal work
• Quick, convenient, and cost-effective method

• Whole animal imaging

• Use the MousePOD accessory to image anesthetized, intact animals and view distribution of the fluorescent probe

• Ex vivo tissue analysis and histology

• Analyze and quantify fluorescent signal in excised tissues or organs, or tissue sections, to determine distribution of the probe

• Simultaneous two-color fluorescence detection

• Flexible imager can perform many applications, including quantitative Western blotting

• IRDye optical probes can also be visualized by fluorescent microscopy

Workflow

Webinars

• Why Image in the NIR?

• "Advances in In Vivo Imaging: Near-Infrared Optical Imaging of Mice" Jeff Harford, LI-COR

• “Instrumentation and Imaging Considerations” Eva Sevick-Muraca, Baylor College of Medicine

• “In vivo imaging of prostate cancer using an IRDye 800CW EGF Optical Probe" Melanie Simpson, University of Nebraska – Lincoln

• “Comparison of visible and near-infrared wavelength-excitable fluorescent dyes for molecular imaging of cancer” Eva Sevick-Muraca and Shi Ke, Baylor College of Medicine

• Development of imaging agents

• “Systematic Evaluation and Use of Targeted IRDye labeled Optical Contrast Agents” Mike Olive, LI-COR

• “Systematic Evaluation of Targeted IRDye Labeled Optical Imaging Agents” Joy Kovar, LI-COR

• “Near Infrared Fluorescent Approaches to Cell-Based Assays and Small Animal Imaging” Amy Geschwender, LI-COR

• Targeted imaging

• "Illuminating Prostate Cancer Progression" Melanie Simpson, University of Nebraska - Eppley Cancer Center

• "IRDye^® 800 2DG: A Broadly Applicable Tumor Imaging Agent for Preclinical Research" Mike Olive, LI-COR

• Five-Part Educational Webinar Series: Optical Imaging

• "Part 1: A Technology Introduction to Optical Imaging"
  Jeff Harford, Senior Product Manager, LI-COR

• "Part 2: A Technical Overview of in vivo Optical Imaging Agents & Targets”
  Peter Johnson, Senior Field Applications Scientist, LI-COR

• "Part 3: A Technical Overview of Optical Imaging: Light Sources & Target Illumination"
  Rex Peterson, Engineering Product Support Manager, LI-COR

• "Part 4: A Technical Overview of Optical Imaging: Dye Absorption & Fluorescence"
  Rex Peterson, Engineering Product Support Manager, LI-COR

• "Part 5: A Technical Overview of Optical Imaging: Light Collection, Imaging Display & Dynamic Range"
  Rex Peterson, Engineering Product Support Manager, LI-COR

Publications

Publishing with LI-COR data?

• Rosenzweig, HL et al.
  Activation of nucleotide oligomerization domain 2 exacerbates a murine model of proteoglycan-induced arthritis.
  J Leukoc Biol. 85(4):711-8 (2009)

• Duysen, EG and Lockridge, O.
  Whole body and tissue imaging of the butyrylcholinesterase knockout mouse injected with near infrared dye labeled butyrylcholinesterase.
  Chem Biol Interact. 175(1-3):119-24 (2008)

• Senf, SM et al.
  Hsp70 overexpression inhibits NF-kappaB and Foxo3a transcriptional activities and prevents skeletal muscle atrophy.
  FASEB J. 22(11):3836-45 (2008)

• He, X et al.
  Cytotoxicity of Paclitaxel in Biodegradable Self-Assembled Core-Shell Poly (Lactide-Co-Glycolide Ethylene Oxide Fumarate) Nanoparticles.
  Pharm Res. 25(7):1552-62 (2008)