Anesthesia: Inhalation vs. Injectable
There are five basic considerations when choosing a method of anesthesia.
- Reduce the likelihood of animal loss
- Avoid interfering with research question
- Minimize the stress to animals
- Maintain a consistent plane of anesthesia through the duration of the procedure
- Have a fast and safe recovery at the end of anesthesia
Upon evaluation of a number of variables, inhalation anesthesia offers many advantages over traditional injectable anesthesia, as seen in the chart below
|
Inhalation |
Injectable |
| Technician expertise |
Low |
High |
| Susceptibility to human error |
Low |
High |
| Stress to the animals |
Low |
High |
| Susceptibility to animal loss |
Low |
High |
| Recovery time for animals |
Short |
Long |
| Labor intensive |
Low |
High |
The SmartFlow Anesthesia Suite provides an effective alternative to traditional injectable anesthesia, while offering a simple and safe environment for the researcher.
How It Works
The SmartFlow Anesthesia Suite's sophisticated design ensures safe and easy anesthesia administration. Flow rates are fixed for each breathing device, eliminating complex calculations and adjustments during procedures as is common with injectable anesthesia as well as traditional inhalation anesthesia systems. Simply specify the concentration and which breathing devices need to be used, and the SmartFlow Anesthesia suite does the rest.
- Oxygen flows from the Oxygen tank into the vaporizer
- Oxygen mixes with Isoflurane producing a specified concentration of gas anesthesia
- Gas anesthesia of a specified concentration flows out at the correct rate for each breathing device
- Gas anesthesia keeps mouse asleep during procedure
- Excess gas is captured by a charcoal filtration device
Video Demonstration
SmartFlow Anesthesia Suite
LI-COR Biosciences SmartFlow Anesthesia Suite is the most advanced inhalation anesthesia design available. The innovative design ensures accurate gas flow for up to five different breathing devices with the simple flip of a switch, eliminating the complex and error prone calculations required on manual systems associated with adjusting the flow rates for multiple breathing systems. Unlike traditional systems, the SmartFlow system accurately controls the flow rate of oxygen for each breathing device which reduces overall costs by more efficient use of oxygen and Isoflurane.
The system accommodates an induction chamber plus up to four other breathing units (e.g. Pearl Impulse, Docking Station, Surgical Suite plus the Odyssey MousePOD Accessory).
Benefits include:
- Preset flow rates reduce the usage of Isoflurane and eliminates the need for flow meters and manual adjustments
- Easy to use on/off switches reduce the chances for operator errors
- Flow rate is not impacted by the number or type of accessories attached to the unit
- Consistent flow rates are obtained over distances greater than 100 feet
- Broad worldwide compatibility with either a 120V Model or 230V Model
SmartFlow Anesthesia Suite Includes:
- SmartFlow Vaporizer Unit
- Charcoal Filters (8)
- Induction Chamber
- Induction Chamber Heater
- Water Pump (120V or 230V)
- Oxygen Regulator (H Tank)
- Filter Stand
- Gas Inflow Hose, Outflow Hose and Oxygen Hose
- Anesthesia Accessories
- Manual and QuickStart Guide
Surgical Suite
The SmartFlow Surgical Suite is an important accessory to LI-COR Biosciences Anesthesia Suite, allowing mice to be safely and easily kept warm (Water Pump not included; water pump is included with SmartFlow Anesthesia Suite) and anesthetized during preparation and surgical procedures. For use on animals up to 500 grams.
SmartFlow Surgical Suite Includes:
- SmartFlow Surgical Bed
- SmartFlow Microflex Non-Rebreather Breathing device
- Filter Stand
- Charcoal Filter
- Two nose cones and plugs
- Surgical Suite Quickstart Guide
Specifications
Anesthesia Suite
SmartFlow Vaporizer
- Oxygen Flush Volume:
30-35 L/m
- Circuit Delivery Volume
- Induction Chamber:
1 L/m ± 10%
- Breathers 1-3 (Pearl® Impulse, Surgical Suite, Docking Station):
0.5 L/M ± 10%
- Breather 4 (MousePOD):
1.5 L/m ± 10%
- Gas Pressure Requirements:
45-55 psi (50psi optimum)
- System Pressure Gauge Range:
0-15 psi
- Dimensions (WxHxD, inches):
13.5 x 11 x 6
- Weight:
~23 lb.
- Material:
- Stand:
Galvanized and Annealed Steel
- Vaporizer:
Brass/Aluminum
- Gas Compatibility:
Isoflurane
- Recommended service intervals:
12-24 months
IMPORTANT NOTE: The Vaporizer on the SmartFlow system is custom designed and MUST NOT be used with any other anesthesia system.
SmartFlow Induction Chamber
- Material:
Acrylic (Do NOT clean with alcohol)
|
SmartFlow Water Pump
- Dimensions (inches):
11.5 x 8 x 8
- Weight (empty):
6.5 lb
- Reservoir capacity:
93 ox (2.75L)
- Flow Rate:
9 gph (34 lph)
- Ambient operating temp:
60°F - 90°F
- Temperature Setpoints:
107°F (42°C)
100°F (38°C)
95°F (35°C)
50°F (10°C)
- Average Temperature Accuracy:
±2°F at 107°F (±1°C at 42°C)
- Maximum Contact Temperature:
107°F (42°C)
- Electrical Requirements (120V)
(For SmartFlow Model 9000-101):
- Voltage (VAC):
120±10%
- Frequency (Hz):
60
- Current (Amps):
3.1 amperes
- Electrical Requirements (230V)
(For SmartFlow Model 9000-102):
- Voltage (VAC):
230±10%
- Frequency (Hz):
50
- Current (Amps):
2.0 amperes
|
Surgical Suite
SmartFlow Sergical Bed
- Dimensions:
10.0"L x 3.7"W x 1.0"H
- Material:
Heavy gauge stainless steel
|
SmartFlow Microflex Rebreather
- Animal size range:
Up to 500 g
|
The SmartFlow product line is distributed through a collaboration between Euthanex Corp. and LI-COR Biosciences. This product line has been tested, designed, and customized to work optimally with the Pearl® Imager, Pearl® Impulse, MousePOD® in vivo Imaging accessory, and the Pearl® Docking Station.
In order to provide the highest level of support, Euthanex Corp. will provide technical support on the SmartFlow product line. Our technical support team would be happy to get you in contact with Euthanex Corp. should the need arise. Please don't hesitate to contact us at (800) 645-4260 or e-mail us at biohelp@licor.com.
