Further Information

Email:
Translational.Research@licor.com

Phone:
(1) 402-467-0904

For preclinical research:
IRDye infrared dyes and imaging probes can be purchased on our Biotechnology website.

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LI-COR Translational Research seeks to facilitate the use of IRDye® 800CW imaging agents in clinical studies for detection of disease and its progression, and for monitoring of treatment and drug efficacy. IRDye 800CW has been conjugated to a variety of targeting agents by leading molecular imaging laboratories developing translatable agents. Unlike indocyanine green, which cannot be attached to biomolecules in its clinically approved form, IRDye 800CW reactive dyes are easily conjugated.

Production of cGMP-compliant material is an important part of the clinical translation process. LI-COR can provide IRDye 800CW produced under cGMP at a scale suitable for smooth transition to clinical studies.

  • LI-COR Announces IRDye® 800CW Near-Infrared Dye Manufactured for Use in Drug Development
    September 8, 2010, Lincoln, Nebraska: LI-COR® Biosciences announces it has completed manufacturing of IRDye® 800CW near-infrared dye under a GMP process. This is considered a key step toward translating near-infrared contrast agents into clinical use... [Read More]

  • LI-COR Biosciences Establishes Translational Research Group
    June 9, 2010, Lincoln, Nebraska: LI-COR® Biosciences announces the establishment of a new Translational Research group to facilitate the use of its IRDye 800CW labeled imaging agents in clinical studies for detection of disease, its progression, and for monitoring treatment and drug efficacy. IRDye 800CW has been conjugated to a variety of preclinical targeting agents by leading molecular imaging laboratories developing translatable agents. Unlike the clinically approved form of indocyanine green (ICG, Cardiogreen®), which cannot be attached to biomolecules, IRDye 800CW reactive dyes are easily conjugated to targeting agents... [Read More]

  • Study Published on Toxicity of IRDye® 800CW Carboxylate
    in Sprague Dawley Rats
    April 21, 2010, Lincoln, NE: In preparation for potential clinical use, a paper reporting a safety and toxicity study of the near infrared dye IRDye® 800CW was reported April 8th in the online section of Molecular Imaging and Biology. The manuscript entitled, “Single-Dose Intravenous Toxicity Study of IRDye 800CW in Sprague-Dawley Rats” reported no pathological evidence of toxicity based on the hematologic, clinical chemistry, and histopathologic analyses performed in the study... [Read More]