Clinical Translation

Recent News

• LI-COR Biosciences Licenses Prostate-targeting Molecular Imaging Agent from The Johns Hopkins University
  September 8, 2011, Lincoln, Nebraska: LI-COR Biosciences has entered into a licensing agreement with The Johns Hopkins University (Baltimore, MD) for compounds and imaging methods targeting prostate-specific membrane antigen (PSMA) developed in the laboratory of Dr. Martin Pomper... [Read More]

• LI-COR Submits Active Substance Master File for IRDye^® 800CW to European
  Regulatory Authorities and Registers Drug Master File with US FDA
  September 1, 2011, Lincoln, Nebraska: LI-COR Biosciences announces an Active Substance Master File (ASMF) for IRDye 800CW N-succidimidyl ester is on record with European regulatory authorities in support of a clinical trial testing a targeted agent for optical imaging-assisted surgery... [Read More]

• LI-COR Announces IRDye^® 800CW Near-Infrared Dye Manufactured for Use in Drug Development
  September 8, 2010, Lincoln, Nebraska: LI-COR^® Biosciences announces it has completed manufacturing of IRDye^® 800CW near-infrared dye under a GMP process. This is considered a key step toward translating near-infrared contrast agents into clinical use... [Read More]

• LI-COR Biosciences Establishes Translational Research Group
  June 9, 2010, Lincoln, Nebraska: LI-COR^® Biosciences announces the establishment of a new Translational Research group to facilitate the use of its IRDye 800CW labeled imaging agents in clinical studies for detection of disease, its progression, and for monitoring treatment and drug efficacy. IRDye 800CW has been conjugated to a variety of preclinical targeting agents by leading molecular imaging laboratories developing translatable agents. Unlike the clinically approved form of indocyanine green (ICG, Cardiogreen^®), which cannot be attached to biomolecules, IRDye 800CW reactive dyes are easily conjugated to targeting agents... [Read More]

• Study Published on Toxicity of IRDye^® 800CW Carboxylate in Sprague Dawley Rats
  April 21, 2010, Lincoln, NE: In preparation for potential clinical use, a paper reporting a safety and toxicity study of the near infrared dye IRDye^® 800CW was reported April 8th in the online section of Molecular Imaging and Biology. The manuscript entitled, "Single-Dose Intravenous Toxicity Study of IRDye 800CW in Sprague-Dawley Rats" reported no pathological evidence of toxicity based on the hematologic, clinical chemistry, and histopathologic analyses performed in the study... [Read More]