Publications: Brain Imaging

Dynamic Near-Infrared Optical Imaging of 2-Deoxyglucose Uptake by Intracranial Glioma of Athymic Mice
Heling Zhou, Kate Luby-Phelps, Bruce E. Mickey, Amyn A. Habib, Ralph P. Mason, Dawen Zhao
Zhou et al. show results for imaging brain tumors with on the IRDye 800 2DG.  The near-infrared dye labeled 2-DG may serve as a novel imaging probe to noninvasively monitor intracranial tumor burden in preclinical animal models.  From a clinical perspective, they suggest the development of NIR labeled tumor-specific molecules may have the potential to identify the infiltrating glioblastoma intra-operatively, and to improve the extent of resection of selected tumors.