Figure 1. Athymic male nu/nu mouse, minutes after receiving IRDye 800CW PEG (~0.1 nmole) intradermally on the tail (right side). Image highlights use of IRDye PEG as a lymph imaging agent. Image captured with the Pearl® Imaging System.
IRDye® 800CW PEG is an effective lymph tracking agent (Figure 1).
- Administer by intradermal injection
- Other contrast agents labeled with IRDye 800CW have been used for intraoperative identification of lymphatic branches and small sentinel lymph nodes, and outperformed NIR quantum dots.1
- The Pearl® Imager Impulse permits rapid time-lapse imaging of vasculature and lymphatics. Watch this two-minute video demonstrating real-time lymphatic and lymph node imaging.
1. Tanaka, E et al. 2006. Ann Surg Oncol. 13(12): 1672-81.