November 24, 2010, Lincoln, NE: LI-COR Biosciences introduces two new IRDye infrared dyes, for fluorescence imaging in the 650 nm and 750 nm regions. IRDye 650 and IRDye 750 NHS Esters are designed for labeling of molecules on primary amine groups. IRDye 650 and IRDye 750 Maleimides allow molecules to be labeled on free sulfhydryl groups. Fluorescent dyes at these wavelengths are well suited for a wide variety of applications, including flow cytometry and fluorescence microscopy.
"Our goal is to provide greater flexibility to researchers working in the 650 and 750 nm ranges Ð specific areas of the near-infrared spectrum that we have not previously supported," says Tony Endozo, LI-COR product manager. "We already offer unique advantages in the 680 and 800 nm ranges with our broad line of IRDye infrared dyes and reagents. The new dyes allow researchers to explore the benefits of fluorescence detection at additional wavelengths."
LI-COR IRDye Infrared Dyes are used with a variety of instrument platforms that offer excitation and emission in the near-infrared spectral region. The 680 nm and 800 nm dye products are specially optimized for use with LI-COR Infrared Imaging Systems. IRDye infrared dyes are ideal for simultaneous, multicolor imaging applications due to the narrow emission spectra of the dyes and lack of crossover between fluorophores.