Glycoprotein Analysis in the Near-Infrared Offers Flexibility and Multiplexing Capabilities
May 22, 2009, Lincoln, NE: Glycoprotein analysis is a growing area of research that requires sensitive and quantitative applications. LI-COR® Biosciences has adapted several one-color, visible glycoprotein applications to near-infrared applications that are detected at 700 nm and 800 nm. Detecting at near-infrared wavelengths provides low background from biological materials, buffer components, and standard membranes used in Western and lectin blotting applications. LI-COR offers a near-infrared system optimized for two-color analysis, which reduces the workload for profiling and characterizing glycoprotein structure.
Several applications for glycoprotein analysis are possible such as glycoprotein gel staining, O-GlcNAc specific antibody detection, glycoprotein labeling, and lectin arrays. The Odyssey® Infrared Imaging System and IRDye® labeled conjugates provide a single optimized solution for detecting a variety of glycoprotein interactions.
About LI-COR Biosciences
Biosciences is a leading manufacturer of near-infrared imaging platforms, analysis software, and LI-COR IRDye® infrared dye reagents for quantitative Western Blotting, small animal imaging, and DNA fragment analysis. The company also offers accessories and reagents for other detection types.
LI-COR pioneered the development of near-infrared fluorescence detection systems for DNA sequencing and today provides systems for drug discovery, protein research, small animal imaging, and undergraduate training. LI-COR instruments for photosynthesis, carbon dioxide analysis and light measurement are recognized worldwide for standard-setting innovation in plant science research and environmental monitoring. Founded in 1971, the privately held company is based in Lincoln, Nebraska, with subsidiaries in Germany and the United Kingdom. LI-COR systems are used in over 100 countries and are supported by a global network of distributors.