IRDye® 680RD Maleimide

Use IRDye 680RD Maleimide to Label Free Sulfhydryls.

IRDye 680RD Maleimide will label molecules with free sulfhydryl (-SH) groups, such as cysteine residues in proteins. Conjugation can be performed at physiological pH.

Which 700 Channel Dye Should I Use?
IRDye® 800CW Maleimide reacting with Thiol group
Which 700 Channel Dye Should I Use?

Dye Structure

IRDye 680RD Maleimide structure


  • Chemical Formula: C45H48CIN5Na2O12S3
  • Molecular Weight: 1028.51 g/mol
  • Exact Mass: 1027.19

Absorption and Emission Spectra

Solvent Ext. Coeff. (M-1cm-1) Absorption Maxima Emission Maxima
Methanol 170,000 680 nm 694 nm
1X PBS 165,000 672 nm 694 nm
PBS: Methanol 165,000

Absorption and Emission Spectra in 1X PBS

IRDye 680RD Absorption and Emission Spectra

To discuss purchase quantities over 1 gram or commercial development rights using IRDye infrared dyes, please contact Business Development.

Selected P/N: 929-71050,929-71051



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